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KMID : 1144320110430030266
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감염과 화학요법
2011 Volume.43 No. 3 p.266 ~ p.269
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Vitamin B12 Deficiency Megaloblastic Anemia in a Patient with Acquired Immunodeficiency Syndrome
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Kim Bong-Young
Kim Ji-Eun
Hwang Soon-woo
Lee Yu-Hwa
Park Jung-Hwan
Moon Shin-Je
Choi Ji-Young
Song Jun-Seok
Jeong Jong-Heon
Pai Hyun-Joo
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Abstract
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Anemia is the most common hematologic finding in patients with advanced infections caused by human immunodeficiency virus (HIV) or advanced acquired immunodeficiency syndrome (AIDS). Among many etiologies of HIVassociated anemia, vitamin B12 deficiency plays an important role, mostly due to malabsorption or HIV enteropathy. We experienced a case of megaloblastic anemia caused by vitamin B12 deficiency in a male patient with an AIDS who had no structural gastrointestinal problem. He showed severe anemia, leukopenia, thrombocytopenia and suspicious neurologic manifestations such as aggravation of dementia and gait disturbance. With vitamin B12 and folate treatment, the patient’s general condition and hematologic features were improved successfully.
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KEYWORD
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Human immunodeficiency virus (HIV), Megaloblastic anemia, Vitamin B12
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